Sophie Mepham PhD

Executive Manager – Research

With more than 20 years of experience in oncology clinical research and a passion for delivering the best care possible, as close to home as possible through new and innovative cancer treatments, Sophie is committed to expanding oncology and haematology clinical trials across Australia, New Zealand and Asia.

Sophie has a Bachelor of Science from the University of Sussex (1995) and a PHD in Oncology/Immunology from the University of Plymouth (2001). She worked in haematology clinical trials for the first eight years of her career at Royal Cornwall Hospitals NHS Trust, managing all clinical research as part of the National Institute for Health Research (NIHR) and successfully leading the first competent authority (MHRA) Good Clinical Practice (GCP)-Compliance Inspection.

Following her move to Australia, Sophie worked for three years as the Senior Manager of Translational and Clinical Research and the Head of the Clinical Trials Unit at the Peter MacCallum Cancer Centre. During this time Sophie also launched one of Australia’s first GCP programs, adapted from the NIHR in the UK to ensure research excellence and regulatory compliance. Prior to joining Icon, Sophie was the National Research Manager at GenesisCare for over three years and supported the development and implementation of innovative clinical research focusing on improving patient outcomes.

Sophie is an NIHR GCP Facilitator Program Lead and has been a university lecturer for many years. She is passionate about dedicating her skills, knowledge and experience to education and ensuring those in research have access to a high level of training. Throughout her career Sophie has been a strong advocate for cancer research in Australia, serving as the Deputy Chair of the Clinical Trial Research Professionals Group within the Clinical Oncology Society of Australia (COSA) and the Chair of the Trans Tasman Radiation Oncology Group (TROG) Clinical Research Education Committee.

In her role as Group Executive – Research, Sophie is committed to providing hope and compassion to cancer patients and their families through increasing access to clinical trials across Australia, New Zealand and Asia.


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